A Review on the Recent Advancements on Therapeutic Effects of Ions in the Physiological Environments

This review focuses on the therapeutic effects of ions when released in physiological environments. Recent studies have shown that metallic like Ag+, Sr2+, Mg2+, Mn2+, Cu2+, Ca2+, P+5, etc., promising results drug delivery systems and regenerative medicine. These can be loaded nanoparticles, mesoporous bioactive glass nanoparticles (MBGNs), hydroxyapatite (HA), calcium phosphates, polymeric coatings, salt solutions. The exhibit different functions environment such as antibacterial, antiviral, anticancer, bioactive, biocompatible, angiogenic effects. Furthermore, metals/metalloid into scaffolds to improve osteoblast proliferation, differentiation, bone development, fibroblast growth, improved wound healing efficacy. Moreover, possess limits. Therefore, further mechanisms need developed for highly controlled sustained release these ions. paper summarizes recent progress use metallic/metalloid medicine encourages study a solution cure diseases.